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   » » Wiki: Angelica Sinensis
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Angelica sinensis, commonly known as dong quai () or female ginseng, is a herb belonging to the family , indigenous to . A. sinensis grows in cool high altitude mountains in East Asia. The yellowish brown root of the plant is harvested in the fall and used in traditional Chinese medicine. There was previously no scientific evidence that A. sinensis is effective for any medicinal purpose. More recently, there have been further studies, with multiple showing that ASP ( Angelica sinensis polysaccharides) has important pharmacological effects, such as antitumor, anemia-improving, anti-inflammatory, antioxidative, immunomodulatory, hepatoprotective, antifibrotic, hypoglycemic, antiradiation, and antiviral effects, the mechanisms of which appear to involve the regulation of inflammation, oxidative stress, and profibrotic signaling pathways.


Cultivation
Angelica is hardy to and can be cultivated at elevations of . Seedlings need to be kept out of direct sunlight, but the mature plant can withstand it. Angelica requires deep moist fertile soil and is perennial if prevented from going to seed.


Traditional Chinese medicine
The dried root of A. sinensis commonly known as Chinese angelica () is widely used in traditional Chinese medicine.


Use and adverse effects
Although A. sinensis has been used safely in doses up to 150 mg daily, there is evidence that it may affect the muscles of the .


Anticoagulant effect
A. sinensis may increase the effects of the drug (as it contains coumarins), and consequently may increase the risk of bleeding. Caution is needed when consumed with herbs (such as or ), which may affect blood clotting.


Phytochemicals
include , , , , cnidilide, isocnidilide, , , and .


See also
  • Chinese herbology
  • Scutellaria baicalensis (Baikal skullcap)
  • Eleutherococcus senticosus or Siberian ginseng

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